@@ -12069,6 +12069,42 @@ (define-public r-anota
the data set is suitable for such analysis.")
(license license:gpl3)))
+(define-public r-anota2seq
+ (package
+ (name "r-anota2seq")
+ (version "1.20.0")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (bioconductor-uri "anota2seq" version))
+ (sha256
+ (base32 "14ggggfa6mdqcb2hfvann9mb66s7a9nxlnh31zblb3mrrjizg1x3"))))
+ (properties `((upstream-name . "anota2seq")))
+ (build-system r-build-system)
+ (propagated-inputs
+ (list r-deseq2
+ r-edger
+ r-limma
+ r-multtest
+ r-qvalue
+ r-rcolorbrewer
+ r-summarizedexperiment))
+ (native-inputs (list r-knitr))
+ (home-page "https://bioconductor.org/packages/anota2seq")
+ (synopsis "Transcriptome-wide analysis of translational efficiency")
+ (description
+ "The anota2seq package provides analysis of translational efficiency and
+differential expression analysis for polysome-profiling and ribosome-profiling
+studies (two or more sample classes) quantified by RNA sequencing or
+DNA-microarray. Polysome-profiling and ribosome-profiling typically generate
+data for two RNA sources, translated mRNA and total mRNA. Analysis of
+differential expression is used to estimate changes within each RNA source.
+Analysis of translational efficiency aims to identify changes in translation
+efficiency leading to altered protein levels that are independent of total mRNA
+levels or buffering, a mechanism regulating translational efficiency so that
+protein levels remain constant despite fluctuating total mRNA levels.")
+ (license license:gpl3)))
+
(define-public r-sigpathway
(package
(name "r-sigpathway")