diff --git a/gnu/local.mk b/gnu/local.mk
index ef1bae5f3c..10ee65fdd5 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1969,6 +1969,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/warsow-qfusion-fix-bool-return-type.patch	\
   %D%/packages/patches/webkitgtk-adjust-bubblewrap-paths.patch	\
   %D%/packages/patches/webrtc-audio-processing-big-endian.patch	\
+  %D%/packages/patches/webrtc-for-telegram-desktop-fix-gcc12-cstdint.patch   \
   %D%/packages/patches/websocketpp-fix-for-cmake-3.15.patch	\
   %D%/packages/patches/widelands-add-missing-map-include.patch	\
   %D%/packages/patches/widelands-system-wide_minizip.patch	\
diff --git a/gnu/packages/patches/webrtc-for-telegram-desktop-fix-gcc12-cstdint.patch b/gnu/packages/patches/webrtc-for-telegram-desktop-fix-gcc12-cstdint.patch
new file mode 100644
index 0000000000..f1fd29d0d3
--- /dev/null
+++ b/gnu/packages/patches/webrtc-for-telegram-desktop-fix-gcc12-cstdint.patch
@@ -0,0 +1,21 @@
+From 86d2bcd7afb8706663d29e30f65863de5a626142 Mon Sep 17 00:00:00 2001
+From: Xiretza <xiretza@xiretza.xyz>
+Date: Sun, 15 May 2022 12:47:41 +0200
+Subject: [PATCH] fix(h265_pps_parser): fix missing cstdint include
+
+---
+ src/common_video/h265/h265_pps_parser.h | 1 +
+ 1 file changed, 1 insertion(+)
+
+diff --git a/src/common_video/h265/h265_pps_parser.h b/src/common_video/h265/h265_pps_parser.h
+index 28c95ea9..c180b1b9 100644
+--- a/src/common_video/h265/h265_pps_parser.h
++++ b/src/common_video/h265/h265_pps_parser.h
+@@ -12,6 +12,7 @@
+ #define COMMON_VIDEO_H265_PPS_PARSER_H_
+
+ #include "absl/types/optional.h"
++#include <cstdint>
+
+ namespace rtc {
+ class BitBuffer;
diff --git a/gnu/packages/telegram.scm b/gnu/packages/telegram.scm
index b67f0358a7..6ae7311cfa 100644
--- a/gnu/packages/telegram.scm
+++ b/gnu/packages/telegram.scm
@@ -30,6 +30,8 @@ (define-module (gnu packages telegram)
   #:use-module (gnu packages digest)
   #:use-module (gnu packages fcitx)
   #:use-module (gnu packages fcitx5)
+  #:use-module (gnu packages freedesktop)
+  #:use-module (gnu packages gl)
   #:use-module (gnu packages glib)
   #:use-module (gnu packages gnome)
   #:use-module (gnu packages gnupg)
@@ -58,6 +60,7 @@ (define-module (gnu packages telegram)
   #:use-module (gnu packages tls)
   #:use-module (gnu packages video)
   #:use-module (gnu packages web)
+  #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xiph)
   #:use-module (gnu packages xorg)
   #:use-module ((guix licenses) #:prefix license:)
@@ -74,35 +77,35 @@ (define-module (gnu packages telegram)
 
 (define %telegram-version "2.9.3")
 
-(define libvpx-for-telegram-desktop
-  (let ((commit "5b63f0f821e94f8072eb483014cfc33b05978bb9")
-        (revision "112"))
+(define libyuv-for-telegram-desktop
+  (let ((commit "ad890067f661dc747a975bc55ba3767fe30d4452")
+        (revision "2211"))
     (origin
       (method git-fetch)
       (uri (git-reference
-            (url "https://chromium.googlesource.com/webm/libvpx")
+            (url "https://chromium.googlesource.com/libyuv/libyuv")
             (commit commit)))
       (file-name (git-file-name
-                  "libvpx-for-telegram-desktop"
-                  (git-version "1.9.0" revision commit)))
+                  "libyuv-for-telegram-desktop"
+                  (git-version "0" revision commit)))
       (sha256
        (base32
-        "1psvxaddihlw1k5n0anxif3qli6zyw2sa2ywn6mkb8six9myrp68")))))
+        "01knnk4h247rq536097n9n3s3brxlbby3nv3ppdgsqfda3k159ll")))))
 
-(define libyuv-for-telegram-desktop
-  (let ((commit "ad890067f661dc747a975bc55ba3767fe30d4452")
-        (revision "2211"))
+(define crc32c-for-telegram-desktop
+  (let ((commit "21fc8ef30415a635e7351ffa0e5d5367943d4a94")
+        (revision "78"))
     (origin
       (method git-fetch)
       (uri (git-reference
-            (url "https://chromium.googlesource.com/libyuv/libyuv")
+            (url "https://github.com/google/crc32c")
             (commit commit)))
       (file-name (git-file-name
-                  "libyuv-for-telegram-desktop"
+                  "crc32c-for-telegram-desktop"
                   (git-version "0" revision commit)))
       (sha256
        (base32
-        "01knnk4h247rq536097n9n3s3brxlbby3nv3ppdgsqfda3k159ll")))))
+        "0cddf8z7v33gfb2k60lkzwa97g20m1v81cnvllm3q9ylpnx8g6f4")))))
 
 (define cmake-helpers-for-telegram-desktop
   (origin
@@ -297,8 +300,8 @@ (define tgcalls-for-telegram-desktop
       "0fvad87hyxli83xn19mgf8jjrrh6y6iaig14pckpbkg33vf4wqkj"))))
 
 (define-public webrtc-for-telegram-desktop
-  (let ((commit "91d836dc84a16584c6ac52b36c04c0de504d9c34")
-        (revision "166"))
+  (let ((commit "621f3da55331733bf0d1b223786b96b68c03dca1")
+        (revision "327"))
     (hidden-package
      (package
        (name "webrtc-for-telegram-desktop")
@@ -314,57 +317,61 @@ (define-public webrtc-for-telegram-desktop
           (file-name
            (git-file-name name version))
           (sha256
-           (base32 "0plwdp6xgxi27hif5j7kpq425cidxyxbbga3z2f64dsninwy5p1x"))
+           (base32 "1ks1572k1jj7pmzwm79p2gdgi31dd4bs761bphnx32zyq4c6skxk"))
+          (patches
+           (search-patches
+            ;; https://github.com/desktop-app/tg_owt/pull/101
+            "webrtc-for-telegram-desktop-fix-gcc12-cstdint.patch"))
           (modules '((guix build utils)
                      (ice-9 ftw)
                      (srfi srfi-1)))
           (snippet
            #~(begin
                (let ((keep
-                      '( ;; Custom forks which are incompatible with the ones in Guix.
-                        "abseil-cpp" "libsrtp" "openh264" "rnnoise"
+                      '("abseil-cpp" "libsrtp" "rnnoise"
                         ;; Not available in Guix.
-                        "pffft" "usrsctp"
-                        ;; Has cmake support files for libvpx input.
-                        "libvpx")))
+                        "crc32c" "pffft")))
                  (with-directory-excursion "src/third_party"
                    (for-each delete-file-recursively
                              (lset-difference string=?
                                               (scandir ".")
-                                              (cons* "." ".." keep)))))))))
+                                              (cons* "." ".." keep)))))
+               ;; Use system openh264.
+               (substitute* "CMakeLists.txt"
+                 (("\\include\\(cmake\\/libopenh264\\.cmake\\)")""))))))
        (build-system cmake-build-system)
        (arguments
-        (list #:tests? #f               ; No target
-              #:configure-flags
-              #~`("-DCMAKE_C_FLAGS=-fPIC"
-                  "-DCMAKE_CXX_FLAGS=-fPIC")
+        (list #:tests? #f       ; No target
               #:phases
               #~(modify-phases %standard-phases
                   (add-after 'unpack 'copy-inputs
                     (lambda _
-                      (let* ((libvpx-to (string-append (getcwd)
-                                                       "/src/third_party/libvpx/source/libvpx"))
-                             (libyuv-to (string-append (getcwd)
-                                                       "/src/third_party/libyuv")))
-                        (copy-recursively #$libvpx-for-telegram-desktop libvpx-to)
-                        (copy-recursively #$libyuv-for-telegram-desktop libyuv-to)))))))
-       (native-inputs (list perl pkg-config python-wrapper yasm))
+                      (copy-recursively
+                       #$libyuv-for-telegram-desktop
+                       (string-append (getcwd) "/src/third_party/libyuv"))
+                      (copy-recursively
+                       #$crc32c-for-telegram-desktop
+                       (string-append (getcwd) "/src/third_party/crc32c/src")))))))
+       (native-inputs (list pkg-config python-wrapper yasm))
        (inputs
-        (list alsa-lib
+        (list abseil-cpp-cxxstd17
               ffmpeg
               libjpeg-turbo
-              glib
-              libxcomposite
-              libxdamage
-              libxrender
-              libxrandr
+              libvpx
+              openh264
               openssl
               opus
-              pipewire
+              ;; TG_OWT_USE_PROTOBUF
               protobuf
-              pulseaudio
-              libx11
+              ;; TG_OWT_USE_PIPEWIRE
+              glib libdrm libglvnd mesa pipewire-0.3
+              ;; TG_OWT_USE_X11
+              libxcomposite
+              libxdamage
               libxext
+              libxfixes
+              libxrandr
+              libxrender
               libxtst))
        (synopsis "WebRTC support for Telegram Desktop")
        (description "WebRTC-for-Telegram-Desktop is a custom WebRTC fork by
@@ -376,13 +383,11 @@ (define-public webrtc-for-telegram-desktop
          license:asl2.0
          ;; LibYuv
          (license:non-copyleft "file:///src/third_party/libyuv/LICENSE")
-         ;; OpenH264
-         license:bsd-2
          ;; PFFFT
          (license:non-copyleft "file:///src/third_party/pffft/LICENSE")
          ;; RnNoise
          license:gpl3
-         ;; LibSRTP, LibVPx, UsrSCTP and Others
+         ;; LibSRTP, Crc32c and Others
          license:bsd-3))))))
 
 (define-public rlottie-for-telegram-desktop
