diff --git a/gnu/local.mk b/gnu/local.mk
index 64a1268fbe..3e94281ccf 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1264,9 +1264,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/gnutls-cross.patch			\
   %D%/packages/patches/gnutls-guile-eintr-eagain.patch		\
   %D%/packages/patches/gobject-introspection-absolute-shlib-path.patch \
-  %D%/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch \
   %D%/packages/patches/gobject-introspection-cc.patch		\
-  %D%/packages/patches/gobject-introspection-cc-1.72.patch	\
   %D%/packages/patches/gobject-introspection-girepository.patch	\
   %D%/packages/patches/go-fix-script-tests.patch			\
   %D%/packages/patches/go-github-com-golang-snappy-32bit-test.patch \
diff --git a/gnu/packages/glib.scm b/gnu/packages/glib.scm
index ecf5cb491f..09386d1652 100644
--- a/gnu/packages/glib.scm
+++ b/gnu/packages/glib.scm
@@ -477,14 +477,14 @@ (define target-name
 (define gobject-introspection
   (package
     (name "gobject-introspection")
-    (version "1.66.1")
+    (version "1.73.1")
     (source (origin
              (method url-fetch)
              (uri (string-append "mirror://gnome/sources/"
                    "gobject-introspection/" (version-major+minor version)
                    "/gobject-introspection-" version ".tar.xz"))
              (sha256
-              (base32 "078n0q7b6z682mf4irclrksm73cyixq295mqnqifl9plwmgaai6x"))
+              (base32 "1gkbx32as3v2286w7k3j24fwhkxj6brr49881m2zavxamfwxdm34"))
              (patches (search-patches
                        "gobject-introspection-cc.patch"
                        "gobject-introspection-girepository.patch"
@@ -564,23 +564,6 @@ (define gobject-introspection
       ;; For tools.
       license:gpl2+))))
 
-(define-public gobject-introspection-next
-  (package
-    (inherit gobject-introspection)
-    (name "gobject-introspection")
-    (version "1.73.1")
-    (source (origin
-              (method url-fetch)
-              (uri (string-append "mirror://gnome/sources/"
-                                  "gobject-introspection/" (version-major+minor version)
-                                  "/gobject-introspection-" version ".tar.xz"))
-              (sha256
-               (base32 "1gkbx32as3v2286w7k3j24fwhkxj6brr49881m2zavxamfwxdm34"))
-              (patches (search-patches
-                        "gobject-introspection-cc-1.72.patch"
-                        "gobject-introspection-girepository.patch"
-                        "gobject-introspection-absolute-shlib-path-1.72.patch"))))))
-
 (define intltool
   (package
     (name "intltool")
diff --git a/gnu/packages/gtk.scm b/gnu/packages/gtk.scm
index 75cf9004b4..f89b0dc199 100644
--- a/gnu/packages/gtk.scm
+++ b/gnu/packages/gtk.scm
@@ -684,7 +684,7 @@ (define-public gtksourceview
      (list `(,glib "bin")               ; for glib-genmarshal, etc.
            gettext-minimal
            gi-docgen
-           gobject-introspection-next
+           gobject-introspection
            pkg-config
            vala
            ;; For testing.
diff --git a/gnu/packages/guile-xyz.scm b/gnu/packages/guile-xyz.scm
index 5d861c5c82..5c7c880b0e 100644
--- a/gnu/packages/guile-xyz.scm
+++ b/gnu/packages/guile-xyz.scm
@@ -2303,7 +2303,7 @@ (define (get lib)
            clutter
            xorg-server-for-tests))
     (propagated-inputs
-     (list gobject-introspection-next))
+     (list gobject-introspection))
     (home-page "https://www.gnu.org/software/g-golf/")
     (synopsis "Guile bindings for GObject Introspection")
     (description
diff --git a/gnu/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch b/gnu/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch
deleted file mode 100644
index 8bb86467c0..0000000000
--- a/gnu/packages/patches/gobject-introspection-absolute-shlib-path-1.72.patch
+++ /dev/null
@@ -1,173 +0,0 @@
-Names of libraries included in typelib files are opened by dlopen.
-Here we add the full path.
-
-This patch was provided by Luca Bruno <lucabru@src.gnome.org>,
-for 'gobject-introspection' 1.40.0 in Nix.
-
-It has since been updated to work with newer versions of
-gobject-introspection.
-
-diff --git a/giscanner/scannermain.py b/giscanner/scannermain.py
-index 1d39ab84..e12ed24e 100644
---- a/giscanner/scannermain.py
-+++ b/giscanner/scannermain.py
-@@ -95,6 +95,39 @@ def get_windows_option_group(parser):
-     return group
- 
- 
-+def _get_default_fallback_libpath():
-+    # Newer multiple-output-optimized stdenv has an environment variable
-+    # $outputLib which in turn specifies another variable which then is used as
-+    # the destination for the library contents (${!outputLib}/lib).
-+    store_path = os.environ.get(os.environ.get("outputLib")) if "outputLib" in os.environ else None
-+    if store_path is None:
-+        outputs = os.environ.get("outputs", "out").split()
-+        if "lib" in outputs:
-+            # For multiple output derivations let's try whether there is a $lib
-+            # environment variable and use that as the base store path.
-+            store_path = os.environ.get("lib")
-+        elif "out" in outputs:
-+            # Otherwise we have a single output derivation, so the libraries
-+            # most certainly will end up in "$out/lib".
-+            store_path = os.environ.get("out")
-+
-+    if store_path is not None:
-+        # Even if we have a $lib as output, there still should be a $lib/lib
-+        # directory.
-+        return os.path.join(store_path, 'lib')
-+    else:
-+        # If we haven't found a possible scenario, let's return an empty string
-+        # so that the shared library won't be prepended with a path.
-+        #
-+        # Note that this doesn't mean that all hope is lost, because after all
-+        # we can still use --fallback-library-path to set one.
-+        #
-+        # Also, we're not returning None, because that would make it very
-+        # difficult to disable adding fallback paths altogether using something
-+        # like: --fallback-library-path=""
-+        return ""
-+
-+
- def _get_option_parser():
-     parser = optparse.OptionParser('%prog [options] sources',
-                                    version='%prog ' + giscanner.__version__)
-@@ -220,6 +253,10 @@ match the namespace prefix.""")
-     parser.add_option("", "--compiler",
-                       action="store", dest="compiler", default=None,
-                       help="the C compiler to use internally")
-+    parser.add_option("", "--fallback-library-path",
-+                      action="store", dest="fallback_libpath",
-+                      default=_get_default_fallback_libpath(),
-+                      help="Path to prepend to unknown shared libraries")
- 
-     group = get_preprocessor_option_group(parser)
-     parser.add_option_group(group)
-diff --git a/giscanner/shlibs.py b/giscanner/shlibs.py
-index 9f8ab5df..8aa37c99 100644
---- a/giscanner/shlibs.py
-+++ b/giscanner/shlibs.py
-@@ -57,6 +57,14 @@ def _ldd_library_pattern(library_name):
-     $""" % re.escape(library_name), re.VERBOSE)
- 
- 
-+def _ldd_library_guix_pattern(library_name):
-+    store_dir = re.escape(
-+      os.environ.get("NIX_STORE", default="/gnu/store")
-+    )
-+    pattern = r'(%s(?:/[^/]*)+lib%s[^A-Za-z0-9_-][^\s\(\)]*)'
-+    return re.compile(pattern % (store_dir, re.escape(library_name)))
-+
-+
- # This is a what we do for non-la files. We assume that we are on an
- # ELF-like system where ldd exists and the soname extracted with ldd is
- # a filename that can be opened with dlopen().
-@@ -108,7 +116,8 @@ def _resolve_non_libtool(options, binary, libraries):
-             output = output.decode("utf-8", "replace")
- 
-         shlibs = resolve_from_ldd_output(libraries, output)
--        return list(map(sanitize_shlib_path, shlibs))
-+        fallback_libpath = options.fallback_libpath or "";
-+        return list(map(lambda p: os.path.join(fallback_libpath, p), map(sanitize_shlib_path, shlibs)))
- 
- 
- def sanitize_shlib_path(lib):
-@@ -117,19 +126,18 @@ def sanitize_shlib_path(lib):
-     # In case we get relative paths on macOS (like @rpath) then we fall
-     # back to the basename as well:
-     # https://gitlab.gnome.org/GNOME/gobject-introspection/issues/222
--    if sys.platform == "darwin":
--        if not os.path.isabs(lib):
--            return os.path.basename(lib)
--        return lib
--    else:
-+
-+    # Always use absolute paths if available
-+    if not os.path.isabs(lib):
-         return os.path.basename(lib)
-+    return lib
- 
- 
- def resolve_from_ldd_output(libraries, output):
-     patterns = {}
-     for library in libraries:
-         if not os.path.isfile(library):
--            patterns[library] = _ldd_library_pattern(library)
-+            patterns[library] = (_ldd_library_pattern(library), _ldd_library_guix_pattern(library))
-     if len(patterns) == 0:
-         return []
- 
-@@ -141,8 +149,12 @@ def resolve_from_ldd_output(libraries, output):
-         if line.endswith(':'):
-             continue
-         for word in line.split():
--            for library, pattern in patterns.items():
--                m = pattern.match(word)
-+            for library, (pattern, guix_pattern) in patterns.items():
-+                store_dir = os.environ.get("NIX_STORE", default="/gnu/store")
-+                if line.find(store_dir) != -1:
-+                    m = guix_pattern.match(word)
-+                else:
-+                    m = pattern.match(word)
-                 if m:
-                     del patterns[library]
-                     shlibs.append(m.group())
-diff --git a/giscanner/utils.py b/giscanner/utils.py
-index 31c7ea48..630002a8 100644
---- a/giscanner/utils.py
-+++ b/giscanner/utils.py
-@@ -114,16 +114,11 @@ def extract_libtool_shlib(la_file):
-     if dlname is None:
-         return None
- 
--    # Darwin uses absolute paths where possible; since the libtool files never
--    # contain absolute paths, use the libdir field
--    if platform.system() == 'Darwin':
--        dlbasename = os.path.basename(dlname)
--        libdir = _extract_libdir_field(la_file)
--        if libdir is None:
--            return dlbasename
--        return libdir + '/' + dlbasename
--    # Older libtools had a path rather than the raw dlname
--    return os.path.basename(dlname)
-+    dlbasename = os.path.basename(dlname)
-+    libdir = _extract_libdir_field(la_file)
-+    if libdir is None:
-+        return dlbasename
-+    return libdir + '/' + dlbasename
- 
- 
- # Returns arguments for invoking libtool, if applicable, otherwise None
-diff --git a/tests/scanner/test_shlibs.py b/tests/scanner/test_shlibs.py
-index a8337c60..7f123103 100644
---- a/tests/scanner/test_shlibs.py
-+++ b/tests/scanner/test_shlibs.py
-@@ -40,7 +40,8 @@ class TestLddParser(unittest.TestCase):
- 
-         self.assertEqual(
-             sanitize_shlib_path('/foo/bar'),
--            '/foo/bar' if sys.platform == 'darwin' else 'bar')
-+            # Always use an absolute filename for Guix
-+            '/foo/bar')
- 
-     def test_unresolved_library(self):
-         output = ''
diff --git a/gnu/packages/patches/gobject-introspection-absolute-shlib-path.patch b/gnu/packages/patches/gobject-introspection-absolute-shlib-path.patch
index 956fa617c3..8bb86467c0 100644
--- a/gnu/packages/patches/gobject-introspection-absolute-shlib-path.patch
+++ b/gnu/packages/patches/gobject-introspection-absolute-shlib-path.patch
@@ -1,11 +1,14 @@
-# Names of libraries included in typelib files are opened by dlopen.  Here we 
-# add the full path.
-#
-# This patch was provided by Luca Bruno <lucabru@src.gnome.org>  for 
-# 'gobject-introspection' 1.40.0 in Nix.
-#
-# It has since been updated to work with newer versions of
-# gobject-introspection.
+Names of libraries included in typelib files are opened by dlopen.
+Here we add the full path.
+
+This patch was provided by Luca Bruno <lucabru@src.gnome.org>,
+for 'gobject-introspection' 1.40.0 in Nix.
+
+It has since been updated to work with newer versions of
+gobject-introspection.
+
+diff --git a/giscanner/scannermain.py b/giscanner/scannermain.py
+index 1d39ab84..e12ed24e 100644
 --- a/giscanner/scannermain.py
 +++ b/giscanner/scannermain.py
 @@ -95,6 +95,39 @@ def get_windows_option_group(parser):
@@ -48,10 +51,10 @@
  def _get_option_parser():
      parser = optparse.OptionParser('%prog [options] sources',
                                     version='%prog ' + giscanner.__version__)
-@@ -205,6 +238,10 @@ match the namespace prefix.""")
-     parser.add_option("", "--filelist",
-                       action="store", dest="filelist", default=[],
-                       help="file containing headers and sources to be scanned")
+@@ -220,6 +253,10 @@ match the namespace prefix.""")
+     parser.add_option("", "--compiler",
+                       action="store", dest="compiler", default=None,
+                       help="the C compiler to use internally")
 +    parser.add_option("", "--fallback-library-path",
 +                      action="store", dest="fallback_libpath",
 +                      default=_get_default_fallback_libpath(),
@@ -59,6 +62,8 @@
  
      group = get_preprocessor_option_group(parser)
      parser.add_option_group(group)
+diff --git a/giscanner/shlibs.py b/giscanner/shlibs.py
+index 9f8ab5df..8aa37c99 100644
 --- a/giscanner/shlibs.py
 +++ b/giscanner/shlibs.py
 @@ -57,6 +57,14 @@ def _ldd_library_pattern(library_name):
@@ -76,7 +81,7 @@
  # This is a what we do for non-la files. We assume that we are on an
  # ELF-like system where ldd exists and the soname extracted with ldd is
  # a filename that can be opened with dlopen().
-@@ -106,7 +112,8 @@ def _resolve_non_libtool(options, binary, libraries):
+@@ -108,7 +116,8 @@ def _resolve_non_libtool(options, binary, libraries):
              output = output.decode("utf-8", "replace")
  
          shlibs = resolve_from_ldd_output(libraries, output)
@@ -86,7 +91,7 @@
  
  
  def sanitize_shlib_path(lib):
-@@ -115,19 +122,18 @@ def sanitize_shlib_path(lib):
+@@ -117,19 +126,18 @@ def sanitize_shlib_path(lib):
      # In case we get relative paths on macOS (like @rpath) then we fall
      # back to the basename as well:
      # https://gitlab.gnome.org/GNOME/gobject-introspection/issues/222
@@ -111,7 +116,7 @@
      if len(patterns) == 0:
          return []
  
-@@ -139,8 +145,12 @@ def resolve_from_ldd_output(libraries, output):
+@@ -141,8 +149,12 @@ def resolve_from_ldd_output(libraries, output):
          if line.endswith(':'):
              continue
          for word in line.split():
@@ -126,10 +131,11 @@
                  if m:
                      del patterns[library]
                      shlibs.append(m.group())
-
+diff --git a/giscanner/utils.py b/giscanner/utils.py
+index 31c7ea48..630002a8 100644
 --- a/giscanner/utils.py
 +++ b/giscanner/utils.py
-@@ -111,17 +111,11 @@ def extract_libtool_shlib(la_file):
+@@ -114,16 +114,11 @@ def extract_libtool_shlib(la_file):
      if dlname is None:
          return None
  
@@ -141,8 +147,7 @@
 -        if libdir is None:
 -            return dlbasename
 -        return libdir + '/' + dlbasename
--    # From the comments in extract_libtool(), older libtools had
--    # a path rather than the raw dlname
+-    # Older libtools had a path rather than the raw dlname
 -    return os.path.basename(dlname)
 +    dlbasename = os.path.basename(dlname)
 +    libdir = _extract_libdir_field(la_file)
@@ -151,10 +156,12 @@
 +    return libdir + '/' + dlbasename
  
  
- def extract_libtool(la_file):
+ # Returns arguments for invoking libtool, if applicable, otherwise None
+diff --git a/tests/scanner/test_shlibs.py b/tests/scanner/test_shlibs.py
+index a8337c60..7f123103 100644
 --- a/tests/scanner/test_shlibs.py
 +++ b/tests/scanner/test_shlibs.py
-@@ -40,6 +64,7 @@ class TestLddParser(unittest.TestCase):
+@@ -40,7 +40,8 @@ class TestLddParser(unittest.TestCase):
  
          self.assertEqual(
              sanitize_shlib_path('/foo/bar'),
@@ -163,4 +170,4 @@
 +            '/foo/bar')
  
      def test_unresolved_library(self):
-output = ''
+         output = ''
diff --git a/gnu/packages/patches/gobject-introspection-cc-1.72.patch b/gnu/packages/patches/gobject-introspection-cc-1.72.patch
deleted file mode 100644
index d3b1df82af..0000000000
--- a/gnu/packages/patches/gobject-introspection-cc-1.72.patch
+++ /dev/null
@@ -1,15 +0,0 @@
-Use gcc as the default C compiler if CC is not set.
-
-diff --git a/giscanner/__init__.py b/giscanner/__init__.py
-index 7c2f365a..607fe341 100644
---- a/giscanner/__init__.py
-+++ b/giscanner/__init__.py
-@@ -21,6 +21,8 @@ import os
- builddir = os.environ.get('UNINSTALLED_INTROSPECTION_BUILDDIR')
- if builddir is not None:
-     __path__.append(os.path.join(builddir, 'giscanner'))  # type: ignore  # mypy issue #1422
-+if not 'CC' in os.environ:
-+    os.environ['CC'] = 'gcc'
- try:
-     from ._version import __version__
- except ImportError:
diff --git a/gnu/packages/patches/gobject-introspection-cc.patch b/gnu/packages/patches/gobject-introspection-cc.patch
index 6a86b56b44..d3b1df82af 100644
--- a/gnu/packages/patches/gobject-introspection-cc.patch
+++ b/gnu/packages/patches/gobject-introspection-cc.patch
@@ -1,12 +1,13 @@
 Use gcc as the default C compiler if CC is not set.
 
-diff -ru gobject-introspection-1.58.1.orig/giscanner/__init__.py gobject-introspection-1.58.1/giscanner/__init__.py
---- gobject-introspection-1.58.1.orig/giscanner/__init__.py	1970-01-01 01:00:00.000000000 +0100
-+++ gobject-introspection-1.58.1/giscanner/__init__.py	2018-12-03 13:33:28.788971299 +0100
-@@ -22,6 +22,8 @@
+diff --git a/giscanner/__init__.py b/giscanner/__init__.py
+index 7c2f365a..607fe341 100644
+--- a/giscanner/__init__.py
++++ b/giscanner/__init__.py
+@@ -21,6 +21,8 @@ import os
  builddir = os.environ.get('UNINSTALLED_INTROSPECTION_BUILDDIR')
  if builddir is not None:
-     __path__.append(os.path.join(builddir, 'giscanner'))
+     __path__.append(os.path.join(builddir, 'giscanner'))  # type: ignore  # mypy issue #1422
 +if not 'CC' in os.environ:
 +    os.environ['CC'] = 'gcc'
  try:
