diff --git a/gnu/local.mk b/gnu/local.mk
index f118fe4442..c8bfe47509 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1799,6 +1799,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/lxc-no-static-bin.patch	\
   %D%/packages/patches/mactelnet-remove-init.patch		\
   %D%/packages/patches/mailutils-variable-lookup.patch		\
+  %D%/packages/patches/mandoc-support-zstd-compression.patch	\
   %D%/packages/patches/make-impure-dirs.patch			\
   %D%/packages/patches/mariadb-rocksdb-atomic-linking.patch	\
   %D%/packages/patches/mathjax-disable-webpack.patch			\
diff --git a/gnu/packages/man.scm b/gnu/packages/man.scm
index 3148fcc8a1..c62568e515 100644
--- a/gnu/packages/man.scm
+++ b/gnu/packages/man.scm
@@ -37,6 +37,7 @@ (define-module (gnu packages man)
   #:use-module (guix build-system gnu)
   #:use-module (guix build-system ruby)
   #:use-module (guix utils)
+  #:use-module (gnu packages)
   #:use-module (gnu packages base)
   #:use-module (gnu packages compression)
   #:use-module (gnu packages dbm)
@@ -273,30 +274,42 @@ (define-public mandoc
               (method url-fetch)
               (uri (string-append "https://mandoc.bsd.lv/snapshots/mandoc-"
                                   version ".tar.gz"))
+              (patches (search-patches "mandoc-support-zstd-compression.patch"))
               (sha256
                (base32
                 "174x2x9ws47b14lm339j6rzm7mxy1j3qhh484khscw0yy1qdbw4b"))))
     (build-system gnu-build-system)
     (arguments
      `(#:test-target "regress"
-       #:phases (modify-phases %standard-phases
-                  (add-before 'configure 'set-prefix
-                    (lambda* (#:key outputs #:allow-other-keys)
-                      (substitute* "configure"
-                        (("^CC=.*")
-                         (string-append "CC=" ,(cc-for-target) "\n"))
-                        (("^DEFCFLAGS=\\\\\"")
-                         "DEFCFLAGS=\"-O2 ")
-                        (("^UTF8_LOCALE=.*")      ;used for tests
-                         "UTF8_LOCALE=en_US.UTF-8\n")
-                        (("^MANPATH_(BASE|DEFAULT)=.*" _ which)
-                         (string-append "MANPATH_" which "="
-                                        "/run/current-system/profile/share/man\n"))
-                        (("^PREFIX=.*")
-                         (string-append "PREFIX=" (assoc-ref outputs "out")
-                                        "\n"))))))))
+       #:make-flags
+       (list "VPATH=./zstd-src/zlibWrapper"
+             (string-join
+               (list "CFLAGS=-DZWRAP_USE_ZSTD=1"
+                     (string-append "-I./zstd-src/zlibWrapper"))
+               " "))
+       #:phases ,#~(modify-phases %standard-phases
+                     (add-after 'unpack 'unpack-zstd
+                       (lambda _
+                         (mkdir "zstd-src")
+                         (invoke "tar" "--strip-components=1" "-C" "zstd-src"
+                                 "-xf" #$(package-source zstd))))
+                     (add-before 'configure 'set-prefix
+                       (lambda* (#:key outputs #:allow-other-keys)
+                         (substitute* "configure"
+                           (("^CC=.*")
+                            (string-append "CC=" #$(cc-for-target) "\n"))
+                           (("^DEFCFLAGS=\\\\\"")
+                            "DEFCFLAGS=\"-O2 ")
+                           (("^UTF8_LOCALE=.*")      ;used for tests
+                            "UTF8_LOCALE=en_US.UTF-8\n")
+                           (("^MANPATH_(BASE|DEFAULT)=.*" _ which)
+                            (string-append "MANPATH_" which "="
+                                           "/run/current-system/profile/share/man\n"))
+                           (("^PREFIX=.*")
+                            (string-append "PREFIX=" (assoc-ref outputs "out")
+                                           "\n"))))))))
     (native-inputs (list (libc-utf8-locales-for-target) perl)) ;used to run tests
-    (inputs (list zlib))
+    (inputs (list zlib (list zstd "lib")))
     (native-search-paths
      (list (search-path-specification
             (variable "MANPATH")
diff --git a/gnu/packages/patches/mandoc-support-zstd-compression.patch b/gnu/packages/patches/mandoc-support-zstd-compression.patch
new file mode 100644
index 0000000000..b8cbeb6782
--- /dev/null
+++ b/gnu/packages/patches/mandoc-support-zstd-compression.patch
@@ -0,0 +1,58 @@
+mandoc upstream does not support zstd compression. However, Guix uses zstd
+compression for its man pages, therefore—without support for this compression
+method—mandoc would be quite useless. Hence, this patchset uses zlibWrapper
+from the zstd project to add zstd compression support to mandoc.
+
+diff -upr mandoc-1.14.6.orig/Makefile mandoc-1.14.6/Makefile
+--- mandoc-1.14.6.orig/Makefile	2025-01-11 16:20:31.511129163 +0100
++++ mandoc-1.14.6/Makefile	2025-01-11 19:16:35.924788821 +0100
+@@ -251,7 +251,12 @@ LIBMANDOC_OBJS	 = $(LIBMAN_OBJS) \
+ 		   msec.o \
+ 		   preconv.o \
+ 		   read.o \
+-		   tag.o
++		   tag.o \
++		   zstd_zlibwrapper.o \
++		   gzclose.o \
++		   gzlib.o \
++		   gzread.o \
++		   gzwrite.o
+ 
+ ALL_COBJS	 = compat_err.o \
+ 		   compat_fts.o \
+Only in mandoc-1.14.6: Makefile.orig
+diff -upr mandoc-1.14.6.orig/configure mandoc-1.14.6/configure
+--- mandoc-1.14.6.orig/configure	2025-01-11 16:20:31.511129163 +0100
++++ mandoc-1.14.6/configure	2025-01-11 19:16:35.924788821 +0100
+@@ -430,7 +430,7 @@ fi
+ [ "${FATAL}" -eq 0 ] || exit 1
+ 
+ # --- LDADD ---
+-LDADD="${LDADD} ${LD_NANOSLEEP} ${LD_RECVMSG} ${LD_OHASH} -lz"
++LDADD="${LDADD} ${LD_NANOSLEEP} ${LD_RECVMSG} ${LD_OHASH} -lz -lzstd"
+ echo "selected LDADD=\"${LDADD}\"" 1>&2
+ echo "selected LDADD=\"${LDADD}\"" 1>&3
+ echo 1>&3
+Only in mandoc-1.14.6: configure.orig
+diff -upr mandoc-1.14.6.orig/read.c mandoc-1.14.6/read.c
+--- mandoc-1.14.6.orig/read.c	2025-01-11 16:35:03.825441715 +0100
++++ mandoc-1.14.6/read.c	2025-01-11 19:16:35.924788821 +0100
+@@ -37,7 +37,7 @@
+ #include <stdlib.h>
+ #include <string.h>
+ #include <unistd.h>
+-#include <zlib.h>
++#include <zstd_zlibwrapper.h>
+ 
+ #include "mandoc_aux.h"
+ #include "mandoc.h"
+@@ -627,7 +627,7 @@ mparse_open(struct mparse *curp, const char *file)
+ 	int		  fd, save_errno;
+ 
+ 	cp = strrchr(file, '.');
+-	curp->gzip = (cp != NULL && ! strcmp(cp + 1, "gz"));
++	curp->gzip = (cp != NULL && (! strcmp(cp + 1, "gz") || ! strcmp(cp + 1, "zst")));
+ 
+ 	/* First try to use the filename as it is. */
+ 
+Only in mandoc-1.14.6: read.c.orig
