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(license license:artistic2.0))) +(define-public r-bandits + (package + (name "r-bandits") + (version "1.12.0") + (source (origin + (method url-fetch) + (uri (bioconductor-uri "BANDITS" version)) + (sha256 + (base32 + "1423djb7cij68y0q2dcp8q7lrcn2fxjn6d25v4qy3w00b2w8ppg9")))) + (properties `((upstream-name . "BANDITS"))) + (build-system r-build-system) + (propagated-inputs + (list r-biocparallel + r-data-table + r-doparallel + r-dorng + r-drimseq + r-foreach + r-ggplot2 + r-mass + r-r-utils + r-rcpp + r-rcpparmadillo)) + (native-inputs (list r-knitr)) + (home-page "https://github.com/SimoneTiberi/BANDITS") + (synopsis "Bayesian analysis of differential splicing") + (description + "@code{BANDITS} is a Bayesian hierarchical model for detecting differential +splicing of genes and transcripts, via @dfn{DTU} (differential transcript usage), +between two or more conditions. The method uses a Bayesian hierarchical framework, +which allows for sample specific proportions in a Dirichlet-Multinomial model, +and samples the allocation of fragments to the transcripts. Parameters are +inferred via @dfn{MCMC} (Markov chain Monte Carlo) techniques and a DTU test is +performed via a multivariate Wald test on the posterior densities for the average +relative abundance of transcripts.") + (license license:gpl3+))) + (define-public r-biocversion (package (name "r-biocversion")