diff --git a/gnu/local.mk b/gnu/local.mk
index c4bd88714c..5dd39924ee 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1644,6 +1644,7 @@ dist_patch_DATA =						\
   %D%/packages/patches/rct-add-missing-headers.patch		\
   %D%/packages/patches/readline-link-ncurses.patch		\
   %D%/packages/patches/readline-6.2-CVE-2014-2524.patch		\
+  %D%/packages/patches/remmina-plugin-path.patch                 \
   %D%/packages/patches/renpy-use-system-fribidi.patch		\
   %D%/packages/patches/reposurgeon-add-missing-docbook-files.patch	\
   %D%/packages/patches/r-httpuv-1.5.5-unvendor-libuv.patch	\
diff --git a/gnu/packages/patches/remmina-plugin-path.patch b/gnu/packages/patches/remmina-plugin-path.patch
new file mode 100644
index 0000000000..ce382be57a
--- /dev/null
+++ b/gnu/packages/patches/remmina-plugin-path.patch
@@ -0,0 +1,79 @@
+From e6e3c454e380bc1e55a719907df43f73f491fca2 Mon Sep 17 00:00:00 2001
+From: Raghav Gururajan <rg@raghavgururajan.name>
+Date: Mon, 10 May 2021 18:21:02 -0400
+Subject: [PATCH] [PATCH]: Change path variable for loading plugins.
+
+Remmina is coded to load plugins from path (REMMINA_RUNTIME_PLUGINDIR)
+provided during compile-time. This causes cycle between outputs 'out'
+and 'plugins'. Therefore, code it to load plugins from path
+(REMMINA_PLUGIN_PATH) provided during run-time.
+---
+ CMakeLists.txt               |  3 ---
+ config.h.in                  |  1 -
+ src/remmina_plugin_manager.c | 10 ++++++----
+ 3 files changed, 6 insertions(+), 8 deletions(-)
+
+diff --git a/CMakeLists.txt b/CMakeLists.txt
+index 17a58b04..acbbe440 100644
+--- a/CMakeLists.txt
++++ b/CMakeLists.txt
+@@ -313,9 +313,6 @@ if(NOT REMMINA_LOCALEDIR)
+ endif()
+ if(NOT REMMINA_PLUGINDIR)
+   set(REMMINA_PLUGINDIR "${CMAKE_INSTALL_FULL_LIBDIR}/remmina/plugins")
+-  if(NOT REMMINA_RUNTIME_PLUGINDIR)
+-    set(REMMINA_RUNTIME_PLUGINDIR "${REMMINA_PLUGINDIR}")
+-  endif()
+ endif()
+ if(NOT REMMINA_UIDIR)
+   set(REMMINA_UIDIR "${REMMINA_DATADIR}/remmina/ui")
+diff --git a/config.h.in b/config.h.in
+index e59bf78a..8e8da940 100644
+--- a/config.h.in
++++ b/config.h.in
+@@ -22,7 +22,6 @@
+ 
+ #define REMMINA_RUNTIME_DATADIR			"${REMMINA_RUNTIME_DATADIR}"
+ #define REMMINA_RUNTIME_LOCALEDIR		"${REMMINA_RUNTIME_LOCALEDIR}"
+-#define REMMINA_RUNTIME_PLUGINDIR		"${REMMINA_RUNTIME_PLUGINDIR}"
+ #define REMMINA_RUNTIME_UIDIR			"${REMMINA_RUNTIME_UIDIR}"
+ #define REMMINA_RUNTIME_THEMEDIR		"${REMMINA_RUNTIME_THEMEDIR}"
+ #define REMMINA_RUNTIME_EXTERNAL_TOOLS_DIR	"${REMMINA_RUNTIME_EXTERNAL_TOOLS_DIR}"
+diff --git a/src/remmina_plugin_manager.c b/src/remmina_plugin_manager.c
+index a1b713a8..74e2c0f0 100644
+--- a/src/remmina_plugin_manager.c
++++ b/src/remmina_plugin_manager.c
+@@ -294,7 +294,7 @@ void remmina_plugin_manager_init()
+ {
+ 	TRACE_CALL(__func__);
+ 	GDir *dir;
+-	const gchar *name, *ptr;
++	const gchar *remmina_plugin_path, *name, *ptr;
+ 	gchar *fullpath;
+ 	RemminaPlugin *plugin;
+ 	RemminaSecretPlugin *sp;
+@@ -312,8 +312,10 @@ void remmina_plugin_manager_init()
+ 		return;
+ 	}
+ 
+-	g_print("Load modules from %s\n", REMMINA_RUNTIME_PLUGINDIR);
+-	dir = g_dir_open(REMMINA_RUNTIME_PLUGINDIR, 0, NULL);
++	remmina_plugin_path = g_getenv("REMMINA_PLUGIN_PATH");
++
++	g_print("Load modules from %s\n", remmina_plugin_path);
++	dir = g_dir_open(remmina_plugin_path, 0, NULL);
+ 
+ 	if (dir == NULL)
+ 		return;
+@@ -323,7 +325,7 @@ void remmina_plugin_manager_init()
+ 		ptr++;
+ 		if (!remmina_plugin_manager_loader_supported(ptr))
+ 			continue;
+-		fullpath = g_strdup_printf(REMMINA_RUNTIME_PLUGINDIR "/%s", name);
++		fullpath = g_strconcat(remmina_plugin_path, "/", name);
+ 		remmina_plugin_manager_load_plugin(fullpath);
+ 		g_free(fullpath);
+ 	}
+-- 
+2.31.1
+
diff --git a/gnu/packages/vnc.scm b/gnu/packages/vnc.scm
index b8979b2921..8530ee97ce 100644
--- a/gnu/packages/vnc.scm
+++ b/gnu/packages/vnc.scm
@@ -29,22 +29,149 @@
   #:use-module (guix utils)
   #:use-module (gnu packages)
   #:use-module (gnu packages autotools)
+  #:use-module (gnu packages avahi)
   #:use-module (gnu packages base)
   #:use-module (gnu packages cmake)
   #:use-module (gnu packages commencement)
   #:use-module (gnu packages compression)
+  #:use-module (gnu packages crypto)
+  #:use-module (gnu packages cups)
   #:use-module (gnu packages fltk)
+  #:use-module (gnu packages freedesktop)
   #:use-module (gnu packages gettext)
+  #:use-module (gnu packages glib)
+  #:use-module (gnu packages gnome)
   #:use-module (gnu packages gnupg)
+  #:use-module (gnu packages gtk)
   #:use-module (gnu packages image)
   #:use-module (gnu packages linux)
+  #:use-module (gnu packages pcre)
   #:use-module (gnu packages perl)
   #:use-module (gnu packages pkg-config)
+  #:use-module (gnu packages rdesktop)
   #:use-module (gnu packages sdl)
+  #:use-module (gnu packages spice)
+  #:use-module (gnu packages ssh)
   #:use-module (gnu packages tls)
+  #:use-module (gnu packages video)
+  #:use-module (gnu packages webkit)
   #:use-module (gnu packages xdisorg)
   #:use-module (gnu packages xorg))
 
+(define-public remmina
+  (package
+    (name "remmina")
+    (version "1.4.16")
+    (source
+     (origin
+       (method git-fetch)
+       (uri
+        (git-reference
+         (url "https://gitlab.com/Remmina/Remmina")
+         (commit (string-append "v" version))))
+       (file-name (git-file-name name version))
+       (patches
+        (search-patches
+         ;; To honor REMMINA_PLUGIN_PATH.
+         "remmina-plugin-path.patch"))
+       (sha256
+        (base32 "09sjsgvh13jnhs6mhj9icyka0ad3qlnkbzvg7djj9rajzaf1y048"))))
+    (build-system cmake-build-system)
+    (outputs '("out" "plugins"))
+    (arguments
+     `(#:tests? #f                      ; No target
+       #:configure-flags
+       (list
+        ;; Install plugins in separate output.
+        (string-append "-DREMMINA_PLUGINDIR="
+                       (assoc-ref %outputs "plugins")
+                       "/lib/remmina/plugins")
+        ;; Disable online version checking.
+        "-DWITH_NEWS=OFF")
+       #:imported-modules
+       (,@%cmake-build-system-modules
+        (guix build glib-or-gtk-build-system))
+       #:modules
+       ((guix build cmake-build-system)
+        ((guix build glib-or-gtk-build-system)
+         #:prefix glib-or-gtk:)
+        (guix build utils))
+       #:phases
+       (modify-phases %standard-phases
+         (add-after 'install 'wrap-progs
+           (lambda* (#:key outputs #:allow-other-keys)
+             (let ((out (assoc-ref outputs "out")))
+               (for-each
+                (lambda (name)
+                  (let ((file (string-append out "/bin/" name))
+                        (gi-typelib-path (getenv "GI_TYPELIB_PATH")))
+                    (wrap-program file
+                      `("GI_TYPELIB_PATH" ":" prefix (,gi-typelib-path)))))
+                '("remmina" "remmina-file-wrapper")))
+             #t))
+         (add-after 'wrap-progs 'glib-or-gtk-compile-schemas
+           (assoc-ref glib-or-gtk:%standard-phases 'glib-or-gtk-compile-schemas))
+         (add-after 'glib-or-gtk-compile-schemas 'glib-or-gtk-wrap
+           (assoc-ref glib-or-gtk:%standard-phases 'glib-or-gtk-wrap)))))
+    (native-inputs
+     `(("gettext" ,gettext-minimal)
+       ("glib:bin" ,glib "bin")
+       ("gobject-introspection" ,gobject-introspection)
+       ("gtk+:bin" ,gtk+ "bin")
+       ("intl" ,intltool)
+       ("pkg-config" ,pkg-config)))
+    (inputs
+     `(("app-indicator" ,libappindicator)
+       ("atk" ,atk)
+       ("avahi" ,avahi)
+       ("cairo" ,cairo)
+       ("cups" ,cups)
+       ("ffmpeg" ,ffmpeg)
+       ("freerdp" ,freerdp)             ; for rdp plugin
+       ("gcrypt" ,libgcrypt)
+       ("gdk-pixbuf" ,gdk-pixbuf+svg)
+       ("glib" ,glib)
+       ("gnome-keyring" ,gnome-keyring)
+       ("gsettings-desktop-schemas" ,gsettings-desktop-schemas)
+       ("gtk+" ,gtk+)
+       ("harfbuzz" ,harfbuzz)
+       ("json-glib" ,json-glib)
+       ("libsecret" ,libsecret)         ; for secret plugin
+       ("libsoup" ,libsoup)
+       ("libssh" ,libssh)               ; for ssh plugin
+       ("libvnc" ,libvnc)               ; for vnc plugin
+       ("openssl" ,openssl)
+       ("pango" ,pango)
+       ("pcre" ,pcre)
+       ("shared-mime-info" ,shared-mime-info)
+       ("sodium" ,libsodium)
+       ("spice-client-gtk" ,spice-gtk)  ; for spice plugin
+       ("telepathy" ,telepathy-glib)    ; for telepathy plugin
+       ("vte" ,vte)
+       ("wayland" ,wayland)
+       ("webkitgtk" ,webkitgtk)         ; for www plugin
+       ("x11" ,libx11)
+       ("xext" ,libxext)                ; for xdmcp plugin
+       ("xdg-utils" ,xdg-utils)
+       ("xkbfile" ,libxkbfile)))        ; for nx plugin
+    (propagated-inputs
+     `(("dconf" ,dconf)))
+    (native-search-paths
+     (list
+      ;; To load plugins when installed via 'plugins' output.
+      (search-path-specification
+       (variable "REMMINA_PLUGIN_PATH")
+       (separator #f)                   ; single entry
+       (files
+        (list
+         "lib/remmina/plugins")))))
+    (search-paths native-search-paths)
+    (home-page "https://remmina.org/")
+    (synopsis "Remote Desktop Client")
+    (description "Remmina is a client to use other desktops remotely.
+RDP, VNC, SPICE, NX, XDMCP, SSH and EXEC network protocols are supported.")
+    (license license:gpl2+)))
+
 (define-public tigervnc-client
   (package
     (name "tigervnc-client")
