diff --git a/Makefile.am b/Makefile.am
index 8a8133d669..c2d71ca5be 100644
--- a/Makefile.am
+++ b/Makefile.am
@@ -150,6 +150,7 @@ MODULES =					\
   guix/build-system/node.scm			\
   guix/build-system/perl.scm			\
   guix/build-system/python.scm			\
+  guix/build-system/renpy.scm			\
   guix/build-system/ocaml.scm			\
   guix/build-system/qt.scm			\
   guix/build-system/waf.scm			\
@@ -205,6 +206,7 @@ MODULES =					\
   guix/build/ocaml-build-system.scm		\
   guix/build/qt-build-system.scm		\
   guix/build/r-build-system.scm			\
+  guix/build/renpy-build-system.scm			\
   guix/build/rakudo-build-system.scm		\
   guix/build/ruby-build-system.scm		\
   guix/build/scons-build-system.scm		\
diff --git a/guix/build-system/renpy.scm b/guix/build-system/renpy.scm
new file mode 100644
index 0000000000..35edc0056d
--- /dev/null
+++ b/guix/build-system/renpy.scm
@@ -0,0 +1,131 @@
+;;; GNU Guix --- Functional package management for GNU
+;;; Copyright © 2021 Leo Prikler <leo.prikler@student.tugraz.at>
+;;;
+;;; This file is part of GNU Guix.
+;;;
+;;; GNU Guix is free software; you can redistribute it and/or modify it
+;;; under the terms of the GNU General Public License as published by
+;;; the Free Software Foundation; either version 3 of the License, or (at
+;;; your option) any later version.
+;;;
+;;; GNU Guix is distributed in the hope that it will be useful, but
+;;; WITHOUT ANY WARRANTY; without even the implied warranty of
+;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+;;; GNU General Public License for more details.
+;;;
+;;; You should have received a copy of the GNU General Public License
+;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
+
+(define-module (guix build-system renpy)
+  #:use-module (guix store)
+  #:use-module (guix utils)
+  #:use-module (guix memoization)
+  #:use-module (guix packages)
+  #:use-module (guix derivations)
+  #:use-module (guix search-paths)
+  #:use-module (guix build-system)
+  #:use-module (guix build-system gnu)
+  #:use-module (ice-9 match)
+  #:use-module (srfi srfi-1)
+  #:use-module (srfi srfi-26)
+  #:export (%renpy-build-system-modules
+            default-renpy
+            renpy-build
+            renpy-build-system))
+
+(define (default-renpy)
+  "Return the default Ren'py package."
+  ;; Lazily resolve the binding to avoid a circular dependency.
+  (let ((module (resolve-interface '(gnu packages game-development))))
+    (module-ref module 'renpy)))
+
+(define %renpy-build-system-modules
+  ;; Build-side modules imported by default.
+  `((guix build renpy-build-system)
+    (guix build json)
+    (guix build python-build-system)
+    ,@%gnu-build-system-modules))
+
+(define* (lower name
+                #:key source inputs native-inputs outputs system target
+                (renpy (default-renpy))
+                #:allow-other-keys
+                #:rest arguments)
+  "Return a bag for NAME."
+  (define private-keywords
+    '(#:source #:target #:renpy #:inputs #:native-inputs))
+
+  (and (not target)                               ;XXX: no cross-compilation
+       (bag
+         (name name)
+         (system system)
+         (host-inputs `(,@(if source
+                              `(("source" ,source))
+                              '())
+                        ,@inputs
+
+                        ;; Keep the standard inputs of 'gnu-build-system'.
+                        ,@(standard-packages)))
+         (build-inputs `(("renpy" ,renpy)
+                         ,@native-inputs))
+         (outputs outputs)
+         (build renpy-build)
+         (arguments (strip-keyword-arguments private-keywords arguments)))))
+
+(define* (renpy-build store name inputs
+                       #:key
+                       (phases '(@ (guix build renpy-build-system)
+                                   %standard-phases))
+                       (configure-flags ''())
+                       (outputs '("out"))
+                       (output "out")
+                       (game "game")
+                       (search-paths '())
+                       (system (%current-system))
+                       (guile #f)
+                       (imported-modules %renpy-build-system-modules)
+                       (modules '((guix build renpy-build-system)
+                                  (guix build utils))))
+  "Build SOURCE using RENPY, and with INPUTS."
+  (define builder
+    `(begin
+       (use-modules ,@modules)
+       (renpy-build #:name ,name
+                    #:source ,(match (assoc-ref inputs "source")
+                                (((? derivation? source))
+                                 (derivation->output-path source))
+                                ((source)
+                                 source)
+                                (source
+                                 source))
+                     #:configure-flags ,configure-flags
+                     #:system ,system
+                     #:phases ,phases
+                     #:outputs %outputs
+                     #:output ,output
+                     #:game ,game
+                     #:search-paths ',(map search-path-specification->sexp
+                                           search-paths)
+                     #:inputs %build-inputs)))
+
+  (define guile-for-build
+    (match guile
+      ((? package?)
+       (package-derivation store guile system #:graft? #f))
+      (#f                                         ; the default
+       (let* ((distro (resolve-interface '(gnu packages commencement)))
+              (guile  (module-ref distro 'guile-final)))
+         (package-derivation store guile system #:graft? #f)))))
+
+  (build-expression->derivation store name builder
+                                #:inputs inputs
+                                #:system system
+                                #:modules imported-modules
+                                #:outputs outputs
+                                #:guile-for-build guile-for-build))
+
+(define renpy-build-system
+  (build-system
+    (name 'renpy)
+    (description "The Ren'py build system")
+    (lower lower)))
diff --git a/guix/build/renpy-build-system.scm b/guix/build/renpy-build-system.scm
new file mode 100644
index 0000000000..464fc97b13
--- /dev/null
+++ b/guix/build/renpy-build-system.scm
@@ -0,0 +1,99 @@
+;;; GNU Guix --- Functional package management for GNU
+;;; Copyright © 2021 Leo Prikler <leo.prikler@student.tugraz.at>
+;;;
+;;; This file is part of GNU Guix.
+;;;
+;;; GNU Guix is free software; you can redistribute it and/or modify it
+;;; under the terms of the GNU General Public License as published by
+;;; the Free Software Foundation; either version 3 of the License, or (at
+;;; your option) any later version.
+;;;
+;;; GNU Guix is distributed in the hope that it will be useful, but
+;;; WITHOUT ANY WARRANTY; without even the implied warranty of
+;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+;;; GNU General Public License for more details.
+;;;
+;;; You should have received a copy of the GNU General Public License
+;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.
+
+(define-module (guix build renpy-build-system)
+  #:use-module ((guix build gnu-build-system) #:prefix gnu:)
+  #:use-module ((guix build python-build-system) #:prefix python:)
+  #:use-module (guix build json)
+  #:use-module (guix build utils)
+  #:use-module (ice-9 match)
+  #:use-module (ice-9 ftw)
+  #:use-module (srfi srfi-1)
+  #:use-module (srfi srfi-26)
+  #:export (%standard-phases
+            renpy-build))
+
+(define* (build #:key game #:allow-other-keys)
+  (for-each make-file-writable
+            (find-files game (lambda (pred stat)
+                               (eq? (stat:type stat) 'directory))))
+  (invoke "renpy"
+          "--json-dump" (string-append game "/renpy-build.json")
+          game
+          ;; should be "compile", but renpy wants to compile itself really
+          ;; badly if we do
+          "quit")
+  #t)
+
+(define* (install #:key outputs game (output "out") #:allow-other-keys)
+  (let* ((out (assoc-ref outputs output))
+         (json-dump (call-with-input-file (string-append game
+                                                         "/renpy-build.json")
+                      read-json))
+         (build (assoc-ref json-dump "build"))
+         (executable-name (assoc-ref build "executable_name"))
+         (directory-name (assoc-ref build "directory_name")))
+    (let ((launcher (string-append out "/bin/" executable-name))
+          (data (string-append out "/share/renpy/" directory-name)))
+      (mkdir-p (string-append out "/bin"))
+      (copy-recursively game data)
+      ;; We don't actually want the metadata to be dumped in the output
+      ;; directory
+      (delete-file (string-append data "/renpy-build.json"))
+      (call-with-output-file launcher
+        (lambda (port)
+          (format port "#!~a~%~a ~a \"$@\""
+                  (which "bash")
+                  (which "renpy")
+                  data)))
+      (chmod launcher #o755)))
+  #t)
+
+(define* (install-desktop-file #:key outputs game (output "out")
+                               #:allow-other-keys)
+  (let* ((out (assoc-ref outputs output))
+         (json-dump (call-with-input-file (string-append game
+                                                         "/renpy-build.json")
+                      read-json))
+         (build (assoc-ref json-dump "build"))
+         (directory-name (assoc-ref build "directory_name"))
+         (executable-name (assoc-ref build "executable_name")))
+    (make-desktop-entry-file
+     (string-append out "/share/applications/" executable-name ".desktop")
+     #:name (assoc-ref json-dump "name")
+     #:generic-name (assoc-ref build "display_name")
+     #:exec (string-append (which "renpy") " "
+                           out "/share/renpy/" directory-name)
+     #:categories '("Game" "Visual Novel")))
+  #t)
+
+(define %standard-phases
+  (modify-phases gnu:%standard-phases
+    (add-after 'unpack 'enable-bytecode-determinism
+      (assoc-ref python:%standard-phases 'enable-bytecode-determinism))
+    (delete 'bootstrap)
+    (delete 'configure)
+    (replace 'build build)
+    (delete 'check)
+    (replace 'install install)
+    (add-after 'install 'install-desktop-file install-desktop-file)))
+
+(define* (renpy-build #:key inputs (phases %standard-phases)
+                       #:allow-other-keys #:rest args)
+  "Build the given Ren'py package, applying all of PHASES in order."
+  (apply gnu:gnu-build #:inputs inputs #:phases phases args))
