diff --git a/gnu/packages/bootstrap.scm b/gnu/packages/bootstrap.scm
index 5a8028a465..260c1b5b91 100644
--- a/gnu/packages/bootstrap.scm
+++ b/gnu/packages/bootstrap.scm
@@ -144,7 +144,16 @@
      ("tar"
       ,(base32 "150c8948cz8r208g6qgn2dn4f4zs5kpgbpbg6bwag6yw42rapw2l"))
      ("xz"
-      ,(base32 "0v5738idy9pqzcbrjdpxi5c6qs5m78zrpsydmrpx5cfcfzbkxzjh")))))
+      ,(base32 "0v5738idy9pqzcbrjdpxi5c6qs5m78zrpsydmrpx5cfcfzbkxzjh")))
+    ("riscv64-linux"
+     ("bash"
+      ,(base32 "0almlf73k6hbm495kzf4bw1rzsg5qddn7z2rf5l3d1xcapac2hj3"))
+     ("mkdir"
+      ,(base32 "0rg1amdcqfkplcy1608jignl8jq0wqzfkp430mwik3f62959gya6"))
+     ("tar"
+      ,(base32 "17d3x27qhiwk7h6ns0xrvbrq0frxz89mjjh2cdwx2rraq5x6wffm"))
+     ("xz"
+      ,(base32 "0nxn75xf386vdq3igmgm8gnyk4h4x0cm8jv71vlb2jvwxh0cyw1q")))))
 
 (define %bootstrap-executable-base-urls
   ;; This is where the bootstrap executables come from.
@@ -159,6 +168,7 @@
     ("powerpc64le-linux" (string-append system "/20210106/" program))
     ("i586-gnu" (string-append system "/20200326/" program))
     ("powerpc-linux" (string-append system "/20200923/bin/" program))
+    ("riscv64-linux" (string-append system "/20210725/bin/" program))
     (_ (string-append system "/" program
                       "?id=44f07d1dc6806e97c4e9ee3e6be883cc59dc666e"))))
 
@@ -362,6 +372,8 @@ or false to signal an error."
                     "/20200326/guile-static-stripped-2.0.14-i586-pc-gnu.tar.xz")
                    ("powerpc64le-linux"
                     "/20210106/guile-static-stripped-2.0.14-powerpc64le-linux-gnu.tar.xz")
+                   ("riscv64-linux"
+                    "/20210725/guile-3.0.2.tar.xz")
                    (_
                     "/20131110/guile-2.0.9.tar.xz"))))
 
@@ -383,7 +395,9 @@ or false to signal an error."
     ("i586-gnu"
      (base32 "0wgqpsmvg25rnqn49ap7kwd2qxccd8dr4lllzp7i3rjvgav27vac"))
     ("powerpc-linux"
-     (base32 "1by2p7s27fbyjzfkcw8h65h4kkqh7d23kv4sgg5jppjn2qx7swq4"))))
+     (base32 "1by2p7s27fbyjzfkcw8h65h4kkqh7d23kv4sgg5jppjn2qx7swq4"))
+    ("riscv64-linux"
+     (base32 "12pqmhsbbp7hh9r1bjdl14l3a4q06plpz6dcks9dysb4czay8p9f"))))
 
 (define (bootstrap-guile-origin system)
   "Return an <origin> object for the Guile tarball of SYSTEM."
@@ -455,6 +469,76 @@ GUILE_SYSTEM_PATH=$out/share/guile/2.0 \
 GUILE_SYSTEM_COMPILED_PATH=$out/lib/guile/2.0/ccache \
 $out/bin/guile -c ~s $out ~a
 
+# Sanity check.
+$out/bin/guile --version~%"
+                                           (derivation->output-path mkdir)
+                                           (derivation->output-path xz)
+                                           (derivation->output-path tar)
+                                           (object->string wrapper)
+                                           (derivation->output-path bash)))))
+    (raw-derivation name
+                    (derivation->output-path bash) `(,builder)
+                    #:system system
+                    #:inputs (map derivation-input
+                                  (list bash mkdir tar xz guile))
+                    #:sources (list builder)
+                    #:env-vars `(("GUILE_TARBALL"
+                                  . ,(derivation->output-path guile))))))
+
+(define* (raw-build-guile3 name inputs
+                    #:key outputs system search-paths
+                    #:allow-other-keys)
+  (define (->store file)
+    (lower-object (bootstrap-executable file system)
+                  system))
+
+  (define (make-guile-wrapper bash guile-real)
+    ;; The following code, run by the bootstrap guile after it is unpacked,
+    ;; creates a wrapper for itself to set its load path.  This replaces the
+    ;; previous non-portable method based on reading the /proc/self/exe
+    ;; symlink.
+    '(begin
+       (use-modules (ice-9 match))
+       (match (command-line)
+         ((_ out bash)
+          (let ((bin-dir    (string-append out "/bin"))
+                (guile      (string-append out "/bin/guile"))
+                (guile-real (string-append out "/bin/.guile-real"))
+                ;; We must avoid using a bare dollar sign in this code,
+                ;; because it would be interpreted by the shell.
+                (dollar     (string (integer->char 36))))
+            (chmod bin-dir #o755)
+            (rename-file guile guile-real)
+            (call-with-output-file guile
+              (lambda (p)
+                (format p "\
+#!~a
+export GUILE_SYSTEM_PATH=~a/share/guile/3.0
+export GUILE_SYSTEM_COMPILED_PATH=~a/lib/guile/3.0/ccache
+exec -a \"~a0\" ~a \"~a@\"\n"
+                        bash out out dollar guile-real dollar)))
+            (chmod guile   #o555)
+            (chmod bin-dir #o555))))))
+
+  (mlet* %store-monad ((tar   (->store "tar"))
+                       (xz    (->store "xz"))
+                       (mkdir (->store "mkdir"))
+                       (bash  (->store "bash"))
+                       (guile (download-bootstrap-guile system))
+                       (wrapper -> (make-guile-wrapper bash guile))
+                       (builder
+                        (text-file "build-bootstrap-guile.sh"
+                                   (format #f "
+echo \"unpacking bootstrap Guile to '$out'...\"
+~a $out
+cd $out
+~a -dc < $GUILE_TARBALL | ~a xv
+
+# Use the bootstrap guile to create its own wrapper to set the load path.
+GUILE_SYSTEM_PATH=$out/share/guile/3.0 \
+GUILE_SYSTEM_COMPILED_PATH=$out/lib/guile/3.0/ccache \
+$out/bin/guile -c ~s $out ~a
+
 # Sanity check.
 $out/bin/guile --version~%"
                                            (derivation->output-path mkdir)
@@ -478,7 +562,9 @@ $out/bin/guile --version~%"
     (name name)
     (system system)
     (build-inputs inputs)
-    (build raw-build)))
+    (build (cond ((target-riscv?)
+                  raw-build-guile3)
+                 (else raw-build)))))
 
 (define %bootstrap-guile
   ;; The Guile used to run the build scripts of the initial derivations.
@@ -518,6 +604,8 @@ $out/bin/guile --version~%"
                                              "/20200326/static-binaries-0-i586-pc-gnu.tar.xz")
                                             ("powerpc-linux"
                                              "/20200923/static-binaries.tar.xz")
+                                            ("riscv64-linux"
+                                             "/20210725/static-binaries.tar.xz")
                                             (_
                                              "/20131110/static-binaries.tar.xz")))
                                      %bootstrap-base-urls))
@@ -544,6 +632,9 @@ $out/bin/guile --version~%"
                               ("powerpc-linux"
                                (base32
                                 "0kspxy0yczan2vlih6aa9hailr2inz000fqa0gn5x9d1fxxa5y8m"))
+                              ("riscv64-linux"
+                               (base32
+                                "0x0xjlpmyh6rkr51p00gp6pscgl6zjida1rsg8vk3rinyi6rrbkg"))
                               ("mips64el-linux"
                                (base32
                                 "072y4wyfsj1bs80r6vbybbafy8ya4vfy7qj25dklwk97m6g71753"))))))
@@ -596,6 +687,8 @@ $out/bin/guile --version~%"
                                              "/20200326/binutils-static-stripped-2.34-i586-pc-gnu.tar.xz")
                                             ("powerpc-linux"
                                              "/20200923/binutils-2.35.1.tar.xz")
+                                            ("riscv64-linux"
+                                             "/20210725/binutils-2.34.tar.xz")
                                             (_
                                              "/20131110/binutils-2.23.2.tar.xz")))
                                      %bootstrap-base-urls))
@@ -616,6 +709,9 @@ $out/bin/guile --version~%"
                               ("powerpc64le-linux"
                                (base32
                                 "1klxy945c61134mzhqzz2gbk8w0n8jq7arwkrvz78d22ff2q0cwz"))
+                              ("riscv64-linux"
+                               (base32
+                                "0n9qf4vbilfmh1lknhw000waakj4q6s50pnjazr5137skm976z5m"))
                               ("i586-gnu"
                                (base32
                                 "11kykv1kmqc5wln57rs4klaqa13hm952smkc57qcsyss21kfjprs"))
@@ -681,6 +777,8 @@ $out/bin/guile --version~%"
                                        "/20200326/glibc-stripped-2.31-i586-pc-gnu.tar.xz")
                                       ("powerpc-linux"
                                        "/20200923/glibc-2.32.tar.xz")
+                                      ("riscv64-linux"
+                                       "/20210725/glibc-2.31.tar.xz")
                                       (_
                                        "/20131110/glibc-2.18.tar.xz")))
                                %bootstrap-base-urls))
@@ -701,6 +799,9 @@ $out/bin/guile --version~%"
                         ("powerpc64le-linux"
                          (base32
                           "1a1df6z8gkaq09md3jy94lixnh20599p58p0s856p10xwjaqr1iz"))
+                        ("riscv64-linux"
+                         (base32
+                          "0d9x80vm7ca1pd2whcmpm1h14zxpb58kqajlxlwffzm04xfsjnxm"))
                         ("i586-gnu"
                          (base32
                           "14ddm10lpbas8bankmn5bcrlqvz1v5dnn1qjzxb19r57vd2w5952"))
@@ -782,6 +883,8 @@ exec ~a/bin/.gcc-wrapped -B~a/lib \
                                         "/20200326/gcc-stripped-5.5.0-i586-pc-gnu.tar.xz")
                                        ("powerpc-linux"
                                         "/20200923/gcc-5.5.0.tar.xz")
+                                       ("riscv64-linux"
+                                        "/20210725/gcc-7.5.0.tar.xz")
                                        (_
                                         "/20131110/gcc-4.8.2.tar.xz")))
                                 %bootstrap-base-urls))
@@ -802,6 +905,9 @@ exec ~a/bin/.gcc-wrapped -B~a/lib \
                          ("powerpc64le-linux"
                           (base32
                            "151kjsai25vz2s667bgzpisx8f281fpl3n9pxz2yrp9jlnadz3m1"))
+                         ("riscv64-linux"
+                          (base32
+                           "1k4mbnb54wj2q37fgshf5dfixixqnhn002vhzvi9pnb57xb9v14d"))
                          ("i586-gnu"
                           (base32
                            "1j2zc58wzil71a34h7c70sd68dmqvcscrw3rmn2whq79vd70zvv5"))
diff --git a/gnu/packages/commencement.scm b/gnu/packages/commencement.scm
index dc9b372132..d395b261c2 100644
--- a/gnu/packages/commencement.scm
+++ b/gnu/packages/commencement.scm
@@ -2496,7 +2496,9 @@ exec " gcc "/bin/" program
        ,@(substitute-keyword-arguments (package-arguments findutils)
            ((#:configure-flags flags ''())
             `(append
-              ,(if (target-64bit?)
+               ;; TODO: Figure out exactly with architectures need this.
+              ,(if (and (target-64bit?)
+                        (not (target-riscv?)))
                    ''("TIME_T_32_BIT_OK=yes")
                    ''())
               ,(match (%current-system)
diff --git a/guix/packages.scm b/guix/packages.scm
index 2349bb4340..7e86da9aae 100644
--- a/guix/packages.scm
+++ b/guix/packages.scm
@@ -366,7 +366,7 @@ name of its URI."
   ;; This is the list of system types that are supported.  By default, we
   ;; expect all packages to build successfully here.
   '("x86_64-linux" "i686-linux" "armhf-linux" "aarch64-linux" "mips64el-linux" "i586-gnu"
-    "powerpc64le-linux" "powerpc-linux"))
+    "powerpc64le-linux" "powerpc-linux" "riscv64-linux"))
 
 (define %hurd-systems
   ;; The GNU/Hurd systems for which support is being developed.
@@ -377,7 +377,7 @@ name of its URI."
   ;;
   ;; XXX: MIPS is unavailable in CI:
   ;; <https://lists.gnu.org/archive/html/guix-devel/2017-03/msg00790.html>.
-  (fold delete %supported-systems '("mips64el-linux" "powerpc-linux")))
+  (fold delete %supported-systems '("mips64el-linux" "powerpc-linux" "riscv64-linux")))
 
 (define-inlinable (sanitize-inputs inputs)
   "Sanitize INPUTS by turning it into a list of name/package tuples if it's
diff --git a/guix/utils.scm b/guix/utils.scm
index 134879feb1..3ca846f075 100644
--- a/guix/utils.scm
+++ b/guix/utils.scm
@@ -707,7 +707,8 @@ architecture (x86_64)?"
 
 (define* (target-64bit? #:optional (system (or (%current-target-system)
                                                (%current-system))))
-  (any (cut string-prefix? <> system) '("x86_64" "aarch64" "mips64" "powerpc64")))
+  (any (cut string-prefix? <> system) '("x86_64" "aarch64" "mips64"
+                                        "powerpc64" "riscv64")))
 
 (define* (cc-for-target #:optional (target (%current-target-system)))
   (if target
diff --git a/m4/guix.m4 b/m4/guix.m4
index e778a56004..c79d3c3bc5 100644
--- a/m4/guix.m4
+++ b/m4/guix.m4
@@ -1,7 +1,7 @@
 dnl GNU Guix --- Functional package management for GNU
 dnl Copyright © 2012, 2013, 2014, 2015, 2016, 2018, 2019, 2020, 2021 Ludovic Courtès <ludo@gnu.org>
 dnl Copyright © 2014 Mark H Weaver <mhw@netris.org>
-dnl Copyright © 2017, 2020 Efraim Flashner <efraim@flashner.co.il>
+dnl Copyright © 2017, 2020, 2021 Efraim Flashner <efraim@flashner.co.il>
 dnl Copyright © 2021 Chris Marusich <cmmarusich@gmail.com>
 dnl
 dnl This file is part of GNU Guix.
@@ -89,7 +89,7 @@ courageous and port the GNU System distribution to it (see
   # Currently only Linux-based systems are supported, and only on some
   # platforms.
   case "$guix_system" in
-    x86_64-linux|i686-linux|armhf-linux|aarch64-linux|powerpc64le-linux|powerpc-linux)
+    x86_64-linux|i686-linux|armhf-linux|aarch64-linux|powerpc64le-linux|powerpc-linux|riscv64-linux)
       ;;
     *)
       if test "x$guix_courageous" = "xyes"; then
